Novel Bifunctional Synthetic Reagents: gem-Dimetallic Compounds Derived from Carbenoid Reagents and Interelement Compounds.

Silylating Agents Derivatization Reagents Protecting-Group Reagents Organosilicon Compounds Analytical Applications Synthetic Applications

NOVEL REAGENTS FOR CREATINE KINASE

The purpose of this investigation was to develop a simple colorimetric method for creatine kinase (CK). The new method is based on the reaction of creatine, formed enzymatically from creatine phosphate and ADP, with different glyoxal compounds. Hydrated glyoxals, such as para-nitrophenyl, 2-thiophene, 4- biphenyl, 4, 4' -biphenyl,α-naphthyl, β-naphthyl, para-chlorophenyl, and styryl were...

Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents

In this review we summarize the most important procedures for the preparation of functionalized organzinc and organomagnesium reagents. In addition, new methods for the preparation of polyfunctional aryl- and heteroaryl zinc- and magnesium compounds, as well as new Pd-catalyzed cross-coupling reactions, are reported herein. Experimental details are given for the most important reactions in the ...

Enantioselective addition of organozinc reagents to carbonyl compounds*

Different chiral camphorsulfonamide derivatives containing a hydroxy or a sulfonamido functionality, as well as chiral 1,2-hydroxysulfonamides, have been evaluated as chiral promoters in the classical enantioselective addition of dialkylzinc reagents to aldehydes in the presence of titanium tetraisopropoxide (ee up to 96 %). Surprisingly, ligands with a structure of isoborneol are able to promo...

Role of Titnium Reagents in Carbonyl Compounds Reactions

This article describes some important organic reactions catalyzed by different titanium-reagents. Combinatorial approach and green procedures involving the use of titanium reagents with other transition-metals (such as Sm, Pd, Sn and Zn) in photochemical procedures, and with the auxiliary techniques like microwaves for environmental friendly reaction conditions, are also discussed.